Endocrine Abstracts

Primary hyperparathyroidism (PHPT) predominantly affects the elderly, with a peak incidence between ages 55 and 70. Parathyroid adenoma is the principal cause, representing 80–85% of all cases. The aim of the study to determine the frequency of parathyroid adenoma in elderly with high parathyroid hormone levels.Subjects and methods: We performed a retrospective analysis of 31 (30 female, 1 male) elderly wih high parathyroid hormone levels. The demog...

Introduction: Dopamine agonists have been reported to increase the risk of cardiac valve regurgitation in valve disease risks for 3 years treatment with cabergoline in patients with prolactinma. The aim of the study was to evaluate the frequency of cardiac valve diseases and regurgitation in patients with prolactinoma at the end of 3 years.Subjects and method: Thirty-one patients with prolactinoma who had received cabergoline following 3 years were enrol...

Incidentalomas (AI) are clinically inapparent adrenal masses. Patients present hormone excess or mass effect, but part of them is clinically silent. They are discovered inadvertently in the course of diagnostic testing or treatment for other clinical conditions. The aim of the study was to investigate the clinical value of tumor size and hormonal status of elderly patients with adrenal incidentaloma (AI).Subjects and Methods: Forty-four elderly with AI w...

Introduction: Hurthle cell of adenoma (HCA)of thyroid gland is rare neoplasms of the thyroid. They have been found in association with various benign thyroid conditions like Hashimoto’s thyroiditis, hyperthyroidism, nodular goiter, and thyroid neoplasms; where they often represent oncocytic metaplasia. Oncocytic cells are also present in normal parathyroid tissue. Oncocytic parathyroid adenomas, predominantly (more than 70%) or exclusively composed of oncocytic cells are ...

Introduction: Low serum levels of 25-hydroxyvitamin D (25(OH)D3) lower than has been reported to be prevalent in several autoimmune diseases. The aims of the study were i) to evaluate the 25(OH)D3 levels in patients with Hashimato’s thyroiditis (HT) and ii) to investigate the relationships between 25(OH)D3, TSH, free T4, free T3, and anti-thyroid peroxidase (anti-TPO) levels in elderly patients with HT.Subjects and method: Stud...

The aims of the study were to determine the frequency of falls in elderly patients with type 2 diabetes mellitus and to evaluate the risk factors for falls. In the study, 100 (mean age 64.9±11.0 years) (65 females, 35 males) elderly patients with type 2 DM were enrolled. Medical record abstraction of sociodemographic, clinical, and laboratory data was performed retrospectively. Medication characteristics, comorbidities, location and height of fall, associated injuries and...

Aims: The metabolic syndrome (MetS) is a summary measure of important CVD risk factors that frequently coexist. The syndrome is evident in 20–30% of middle-aged women and has been linked to the development of CVD and diabetes. The aim of the study was to examine the differences in demographic and clinical profiles among older (≥60 years) and younger (<60 years) patients with MetS.Methods: The study was included 45 older (mean age 63.1&#177...

Objective: In recent years, many studies have been conducted on the beneficial effects of vitamin D. Vitamin D have many important effects on calcium metabolism, skeletal system and also on different systems. Low serum vitamin D levels are predictors of type 2 diabetes mellitus, cancer, cardiovascular diseases, immunological diseases and even mortality. The relationships between vitamin D and cardiovascular diseases can be explained by the lipid-lowering effect of vitamin D. I...

Introduction: Autoimmune polyglandular syndrome type 2 (APS2) is the most common form of the polyglandular failure syndromes. Seventy-five percent of cases occur in women. Adrenal insufficiency is the principal manifestation occurs with autoimmune thyroid disease or type I diabetes mellitus. The incidence of autoimmune thyroid diseases in APS2 is 70%; 30% Hashimoto’s thyroiditis, 20% non toxic goiter, 20% hypertyroidism is seen. We will discuss about a patient with APS2, ...

Purpose: The purpose of this study was to analyse ghrelin concentrations in the umbilical cord of pregnant women with a diagnosis of gestational diabetes mellitus. The relationship between ghrelin concentrations and birth weights was investigated.Methods: Sixty pregnant women with gestational diabetes mellitus and 64 healthy pregnant women with three oral glucose tolerance test results within normal limits were included in the study. Following birth but ...